Growth hormone (GH), also called somatotropin or human growth hormone (HGH), is a substance in the body that helps children grow and develop. In biochemical terms, GH stimulates protein synthesis and increases fat breakdown to provide the energy necessary for tissue growth. It is produced by the pituitary gland present in the brain, responsible for producing many hormones.
It also helps keep your tissues and organs healthy throughout life. At the age of 40 to 60, the pituitary gland gradually reduces the production of growth hormones. This hormone can help to speed up healing after an injury and repair muscle tissue after exercise. This helps to build muscle mass, boost metabolism, and burn fat.
Types of GH
- Somatotropin is the other name for growth hormone 1, which is produced naturally in animals.
- Somatropin is the synthetic form of growth hormone that is synthesized using recombinant DNA technologies. It is also referred to under the brand name Humatrope.
Deficiency of GH (Growth Hormone)
There are two types of growth hormone deficiency:
First, congenital in which the child suffers from this problem along with birth. Even though they are born with the condition, some babies look like they are generally growing until they are about 6 to 12 months old. They may also have problems with other hormones.
Second, growth hormone deficiency occurs when the body stops making enough growth hormone to grow normally. It can start at any time in childhood.
Symptoms of GH Deficiency
Adults with growth hormone deficiency may have symptoms including:
- poor bone density (which can lead to osteoporosis if untreated)
- reduced muscle mass
- poor memory
- increased body fat around the waist.
Children with growth hormone deficiency may have symptoms including:
- Short height,
- Delayed puberty,
- Late teething,
- Delayed nail growth,
- Muscle weakness,
- Loss of energy,
- Small penis at birth in boys,
- Low blood sugar
In some cases, GH deficiency is the result of GHRH deficiency, in which case GH secretion may be stimulated by infusion of GHRH.
Side effects of growth hormone use
people who use synthetic growth hormone may have these side effects:
- fluid retention (which leads to swelling in the arms and legs)
- joint and muscle pain
- carpal tunnel syndrome
- high blood sugar levels
- high cholesterol levels.
Growth hormone injection treatment is prescribed for children who have been diagnosed with growth hormone (GH) deficiency and other conditions causing short stature.
In children, GH is used to treat:
- Growth hormone deficiency
- Conditions that cause short stature, such as chronic kidney disease, Turner syndrome, and Prader-Willi syndrome
In adults, GH is used to treat:
- Growth hormone deficiency
- Muscle wasting from HIV
- Short bowel syndrome